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Table 1 Patients’ characteristics (data are shown as mean ± SD)

From: Quantitative imaging parameters to predict the local staging of prostate cancer in intermediate- to high-risk patients

 

Total

EPD + 

EPD-

p-value

Number of patients

73

31

42

 

Age (years)

64.5 ± 6 (51–78)

66.3 ± 5.4 (53–76)

63.2 ± 6.2 (51–78)

0.026

PSA before PET/MRI (ng/ml)

14.4 ± 17.1 (1.2–104)

22 ± 20 (2.1–104)

10.3 ± 10.2 (1.22–55)

0.031

MRI (n)

 Internal–external

55–18

18–13

37–5

 

 1.5–3.0 T

2–71

1–30

1–41

 

 Endorectal coil–No coil

8–65

6–25

2–40

 

Time between mpMRI and PET

 Days

64.6 ± 50.5 (0–175)

65.5 ± 48.1 (0–174)

63.9 ± 52.2 (0–175)

0.729

Clinical T stage (n)

 

0.052

  

 T1

46/73 (63%)

16/31 (52%)

30/42 (71.5%)

 

 T2

24/73 (32.5%)

12/31 (38.5%)

12/42 (28.5%)

 

 T3

2/73 (3%)

2/31(6.5%)

0/42 (0%)

 

 T4

1/73 (1.5%)

1/31 (3%)

0/42 (0%)

 

ISUP biopsy grade n (%)

 

0.220

  

 1

2/73 (3%)

0/31 (0%)

2/42 (5%)

 

 2

10/73 (14%)

6/31 (19.5%)

4/42 (10%)

 

 3

15/73 (20%)

4/31 (13%)

11/42 (26%)

 

 4

30/73 (41%)

10/31 (32%)

20/42 (47%)

 

 5

16/73 (22%)

11/31 (35.5%)

5/42 (12%)

 

Time between PET and RPE

 Days

38.3 ± 31.2 (1–177)

36.2 ± 23.2 (3–93)

39.9 ± 35.9 (1–177)

0.969

ISUP RPE grade n (%)

   

 < 0.001

 1

0/73 (0%)

0/31 (0%)

0/42 (0%)

 

 2

9/73 (12.5%)

3/31 (10%)

6/42 (14%)

 

 3

28/73 (38.5%)

5/31 (16%)

23/42 (55%)

 

 4

17/73 (23%)

8/31 (26%)

9/42 (21%)

 

 5

19/73 (26%)

15/31 (48%)

4/42 (10%)

 
  1. Statistically significant p-values are marked by bold font
  2. EPD extraprostatic disease (on RPE specimen); SD standard deviation; mpMRI multiparametric magnetic resonance imaging; PET positron emission tomography/magnetic resonance imaging; PSA prostate-specific antigen; ISUP international society of urological pathology; and RPE radical prostatectomy