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Table 1 Patient distribution according to clinicopathological and radiologic factors

From: Recurrence dynamics after curative surgery in patients with invasive mucinous adenocarcinoma of the lung

No. of patients

Total = 121

Clinical factor

Sex (%)

 Male

56 (46.3)

 Female

65 (53.7)

Age, median (IQR)

58 (52–68)

Smoking (%)

 Never

82 (67.8)

 Ever

39 (32.2)

Surgical procedure (%)

 Sublobar resection

8 (6.6)

 Lobectomy

113 (93.4)

Neoadjuvant or adjuvant treatment (%)

 No

92 (76)

 Yes

29 (24.0)

CT factor

CT morphology (%)

 Nodular type

91 (75.2)

 Consolidative type

30 (24.8)

Solidity (%)

 Solid

63 (52.1)

 Part-solid

58 (47.9)

 Well-defined heterogenous GGO (%)

15 (12.4)

 Lobulated margin (%)

47 (38.8)

 Spiculated margin (%)

38 (31.4)

 CT air-bronchogram (%)

70 (57.9)

 CT angiogram sign (%)

25 (20.7)

Pathologic factor

Surgical bronchial margin (%)

 > 1 cm

98 (81)

 ≤ 1 cm

9 (7.4)

NA

14 (11.6)

T stage (%)

1.6 (0.5)

1A/B

53 (43.8)

2A/B

67 (55.4)

3

1 (0.8)

N stage (%)

 0

106 (87.6)

 1

5 (4.1)

 2

10 (8.3)

 No. of LNs dissected, median (IQR)

15 (9–21)

TNM stage (%)

 I

82 (67.8)

 II

24 (19.8)

 III

15 (12.4)

Tumor differentiation (%)

 Well

89 (73.6)

 Moderate

25 (20.7)

 Poor

7 (5.8)

Aerogenous spread (%)

 No

52 (43.0)

 Yes

62 (51.2)

 NA

7 (5.8)

Mucin (%)

 No

39 (32.2)

 Yes

71 (58.7)

 NA

11 (9.1)

STAS (%)

 No

31 (25.6)

 Yes

79 (65.3)

 NA

11 (9.1)

EGFR mutation (%)

 No

11 (9.1)

 Yes

21 (17.3)

 NA

89 (73.6)

Prognosis

OS event, yes

(median follow-up period 81.4 [IQR, 41.8–109.5 months])

31 (25.6)

DFS event, yes

(median follow-up period 59.8 [IQR, 24.6–104.6 months])

35 (28.9)

  1. IQR interquartile range, CT computed tomography, GGO ground glass opacity, LN lymph node, NA not available, STAS spread through air spaces, EGFR epidermal growth factor receptor, OS overall survival, DFS disease-free survival