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Table 1 Participants’ demographic, clinical and MRI parameters and their statistical analysis

From: The utility of splenic imaging parameters in cardiac magnetic resonance for the diagnosis of immunoglobulin light-chain amyloidosis

Variables

Cardiac amyloidosis (n = 34)

LVH in AS (n = 32)

p value between CA and LVH-AS

Age (IQR)

67.5 (60–73)

68 (59–76)

0.98

Body surface area (IQR)

1.9 (1.6–2)

1.9 (1.8–2)

0.28

SBP, mmHg (IQR)

116 (110–130)

130 (120–145)

0.009

DBP, mmHg (IQR)

70 (70–80)

80 (70–88)

0.14

Males (%)

61.9%

66.7%

0.2

Maximum LV wall thickness, mm (IQR)

15 (12–18)

16 (13–17)

0.9

LV mass/BSA, g/m2 (IQR)

77.5 (59–94)

78.3 (59.3–97.8)

0.8

LV EDV, ml (IQR)

144.5 (107–170)

75.4 (57.3–100.1)

< 0.001

LV ESV, ml (IQR)

56.5 (31–74)

29 (14.8–43.4)

0.001

LV SV, ml (IQR)

83 (67–95)

46.6 (39.8–57.3)

0.001

LV CO/BSA, ml/m2 (IQR)

3.2 (0.7)

3.2 (1.3)

0.6

LVEF, %

61 (55–71)

65 (54–78)

0.4

T1 spleen, ms (IQR)

1392.5 (1346–1455)

1391 (1325–1445)

0.9

T2 mapping Spleen, ms (IQR)

80 (59–92)

79.5 (71.4–91.5)

0.8

ECV spleen %, (IQR)

47 (32–60)

31 (29–34)

< 0.001

STIR ratio spleen, (IQR)

1.7 (1.4–2.5)

2.7 (2.3–3.5)

< 0.001

  1. CA cardiac amyloidosis, LVH-AS left ventricular hypertrophy in the setting of aortic stenosis, BSA body surface area, LV left ventricular, IQR interquartile range, SBP systolic blood pressure, DBP diastolic blood pressure, EDV end diastolic volume, ESV end systolic volume, SV stroke volume, CO cardiac output, EF ejection fraction, ECV extracellular volume, STIR short tau inversion recovery