Noninvasive assessment of clinical and pathological characteristics of patients with IgA nephropathy by diffusion kurtosis imaging

Insights into Imaging

Table 4 Correlations between the diffusional kurtosis imaging (DKI) metrics and clinicopathological data

	MK				MD				ADC
	Cortex		Medulla		Cortex		Medulla		Cortex		Medulla
	r	P	r	P	r	P	r	P	r	P	r	P
CKD stages	0.749	< 0.001	0.686	< 0.001	− 0.499	0.001	− 0.092	0.563	− 0.635	< 0.001	− 0.419	0.006
eGFR	− 0.753	< 0.001	− 0.662	< 0.001	0.470	0.002	0.154	0.331	0.572	< 0.001	0.381	0.013
SCr	0.781	< 0.001	0.752	< 0.001	− 0.485	0.001	− 0.135	0.394	− 0.606	< 0.001	− 0.440	0.004
Uric- acid	0.485	0.001	0.496	0.001	− 0.397	0.009	− 0.180	0.253	− 0.425	0.005	− 0.224	0.153
BUN	0.730	< 0.001	0.587	< 0.001	− 0.322	0.038	− 0.122	0.441	− 0.400	0.009	− 0.296	0.057
Total score	0.516	0.005	0.437	0.023	− 0.506	0.006	− 0.410	0.030	− 0.532	0.004	− 0.251	0.197
Glomerular lesion score	0.497	0.007	0.430	0.025	− 0.509	0.006	− 0.398	0.036	− 0.442	0.018	− 0.273	0.159
Tubulointerstitial lesion score	0.548	0.003	0.499	0.008	− 0. 471	0.011	− 0.398	0.036	− 0.541	0.003	− 0.261	0.179
Vascular lesion score	0.135	0.493	0.177	0.378	− 0.130	0.508	− 0.094	0.634	− 0.219	0.262	− 0.094	0.635
Interstitial fibrosis	0.489	0.008	0.545	0.003	− 0.526	0.004	− 0.269	0.166	− 0.513	0.005	− 0.173	0.379
Tubular atrophy	0.596	0.001	0.536	0.004	− 0.487	0.009	− 0.370	0.053	− 0.438	0.020	− 0.189	0.334
Interstitial inflammatory cell infiltration	0.576	0.001	0.482	0.011	− 0.316	0.102	− 0.287	0.139	− 0.546	0.003	− 0.245	0.210