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Table 1 Patient demographics and tumor characteristics in the endometrial cancer study cohort (n = 357)

From: MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer

 

Entire cohort

Dichotomized with iTFD-cutoff < / ≥ 6 mm

iTFD ≥ 6 mm

iTFD < 6 mm

p valueα

Age, median (range), years

67 (30–93)

64 (32–93)

70 (30–89)

 < 0.001

BMI, median (range), kg/m2

27 (16–53)

28 (16–53)

27 (16–50)

0.03

Postmenopausal, n (%)

327 (92)

171 (87)

156 (98)

 < 0.001

FIGO stage, n (%)

   

0.003

 1 & 2

307 (86)

179 (91)

128 (80)

 

 3 & 4

50 (14)

18 (9)

32 (20)

 

Myometrial invasion, n (%)*

   

 < 0.001

 < 50%

211 (60)

162 (83)

49 (32)

 

 ≥ 50%

139 (40)

33 (17)

106 (68)

 

Cervical stroma invasion, n (%)*

   

0.001

 No

299 (85)

177 (91)

122 (79)

 

 Yes

51 (15)

18 (9)

33 (21)

 

Lymph node metastasis, n (%)**

   

0.16

 No

213 (87)

112 (90)

101 (83)

 

 Yes

33 (13)

13 (10)

20 (17)

 

Histological type, n (%)

   

0.79

 Endometrioid

290 (81)

161 (82)

129 (81)

 

 Non-endometrioid

 

67 (19)

36 (18)

31 (19)

Histological grade in endometrioid tumors, n (%)***

   

 < 0.001

 Grade 1

160 (56)

102 (65)

58 (45)

 

 Grade 2

77 (27)

42 (27)

35 (27)

 

 Grade 3

50 (17)

14 (9)

36 (28)

 
  1. All significant p values are given in boldface
  2. BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; iTFD, tumor-free distance to serosa based on imaging findings
  3. *Missing information in seven patients who did not undergo hysterectomy
  4. **Missing information in 111 patients who did not undergo lymphadenectomy
  5. ***Missing information on tumor grade in three patients
  6. αp values (asymptotic) refer to Pearson Chi-squared test for categorical variables and Mann–Whitney U-test for continuous variables