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Table 1 Classification and physicochemical characteristics of ICM

From: Preprocedural fasting for contrast-enhanced CT: when experience meets evidence

Classification

Structure

Generic name

Brand name

Molecular weight

aIodine content

bOsmotic pressure

cViscosity

First generation (HOCM)

Ionic monomer

Ditriazoate

Meglumine diatrizoate

809

306

1530

5.0

Second generation (LOCM)

Nonionic monomer

Iohexol

Ominpaque

821

300, 350

680, 830

6.3, 10.4

Iopamidol

Iopamiro

777

300, 370

616, 796

4.7, 9.4

Iopromide

Ultravist

791

300, 370

590, 770

4.7, 10.0

Ioversol

Optiray

807

320, 350

710, 790

5.8, 9.0

Iobitridol

Xenetix

835

300, 350

695, 915

6.0, 10.0

Iomeprol

Iomeron

777

300, 400

521, 726

 

Ionic dimer

Ioxaglate

Hexabrix

1270

320

600

7.5

Third generation (IOCM)

Nonionic dimer

Iodixanol

Visipaque

1550

270, 320

290, 290

5.8, 11.8

Iotrolan

Isovist

1626

300

290

 
  1. HOCM, high-osmolality contrast media; LOCM, low-osmolality contrast media; IOCM, iso-osmolality contrast media
  2. amg I/mL
  3. bmOsm/kg H2O
  4. cmPa.s/37℃