Fig. 2From: Factors affecting the value of diffusion-weighted imaging for identifying breast cancer patients with pathological complete response on neoadjuvant systemic therapy: a systematic reviewMean/median ADC-values (× 10−3 mm2/s) in different studies pre, during and post-NST between the pCR group (left figure) and the non-pCR group (right figure). Different time points are connected by solid (: studies acquired at 1.5 T), dashed (: studies acquired at 3.0 T) lines. Hahn et al. and Partridge et al. used both 1.5 T and 3.0 T scanners represented with non-connected points. The legend shows different studies that are included in the graphs. Note: the period of a cycle of neoadjuvant therapy (number of weeks) can differ and within and between studies as well as the total number of cycles. Subsequently, the solid, and dashed arrow lines should not be used for interpolation of ADC-values between two measuring time points. For Woodhams et al. [64] only the pCR-definition from the full-text was used, ADC rounded at one decimal. For Kim et al. [53] Miller and Payne grade 4 as good responders includedBack to article page