Table 6 Predictive performance of combined model, radiomics model, and clinicoradiological model
Model | Combined model | Radiomics model | Clinicoradiological model | ||||||
|---|---|---|---|---|---|---|---|---|---|
Training cohort | Validation cohort | Testing cohort | Training cohort | Validation cohort | Testing cohort | Training cohort | Validation cohort | Testing cohort | |
AUC | 0.887 [0.798–0.952] | 0.859 [0.748–0.935] | 0.828 [0.731–0.929] | 0.860 [0.759–0.963] | 0.824 [0.736–0.915] | 0.787 [0.710–0.892] | 0.752 [0.649–0.870] | 0.703 [0.592–0.844] | 0.637 [0.511–0.769] |
Accuracy (%) | 85.24 [76.75–90.14] | 82.76 [75.99–91.36] | 81.62 [74.18–92.45] | 83.61 [75.85–92.65] | 77.14 [69.38–86.05] | 73.42 [61.63–82.66] | 69.33 [56.54–83.76] | 62.87 [51.74–75.36] | 56.35 [42.48–69.49] |
Sensitivity (%) | 89.77 [80.63–96.98] | 84.94 [76.72–92.49] | 85.56 [77.82–91.58] | 84.78 [74.36–93.74] | 78.72 [64.35–91.48] | 82.15 [73.74–91.92] | 71.86 [59.43–83.82] | 73.89 [65.95–83.47] | 65.78 [46.89–80.87] |
Specificity (%) | 84.47 [72.60–91.65] | 83.42 [74.32–92.18] | 78.01 [69.45–85.74] | 82.67 [74.35–93.14] | 80.33 [69.74–92.26] | 76.48 [63.36–89.17] | 70.42 [61.36–83.47] | 66.86 [56.63–78.10] | 64.23 [52.36–80.62] |
PPV (%) | 82.34 [73.87–91.59] | 81.52 [73.67–87.59] | 78.36 [70.16–86.47] | 77.79 [69.16–85.97] | 75.98 [68.30–83.57] | 74.82 [65.87–83.64] | 68.24 [56.25–81.39] | 65.71 [52.63–78.78] | 60.99 [48.34–73.76] |
NPV (%) | 87.65 [79.48–97.86] | 86.77 [78.43–91.17] | 85.60 [79.98–90.35] | 83.90 [72.74–95.46] | 80.43 [71.32–89.91] | 82.62 [71.64–92.35] | 74.22 [65.61–86.34] | 70.98 [61.05–82.77] | 73.17 [60.05–87.47] |