Single-center versus multi-center biparametric MRI radiomics approach for clinically significant peripheral zone prostate cancer

Insights into Imaging

Table 5 AUCs for the test results and external validation of the single-center, single-vendor model and the multi-center, multi-vendor model

	Single-center, single-vendor model	Multi-center, multi-vendor model	p value
Single-center validation (AUC)	0.82 (95% CI 0.71–0.92)	0.66 (95% CI 0.56–0.75)	0.03
Multi-center validation (AUC)	0.59 (95% CI 0.51–0.68)	0.75 (95% CI 0.64–0.84)	0.012
Percentage change	− 27.2%	− 12%	x
p value	0.002	0.114

Percentage change refers to the change in performance for the development validation and external validation. For the single-center model, this means the change from single-center validation to multi-center validation, and for the multi-center model this mean the change from multi-center validation to single-center validation