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Table 5 Correlation of clinical data and MRI- derived parameters

From: Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging

  T2* ADC Dt
Cortex Medulla Cortex Medulla Cortex
r P r P r P r P r P
eGFR 0.824  < 0.001 0.619  < 0.001 0.517  < 0.001 0.482  < 0.001 0.506  < 0.001
Serum creatinine −0.474  < 0.001 −0.350 0.002 −0.551  < 0.001 −0.475  < 0.001 −0.481  < 0.001
ACR −0.304 0.008 −0.370 0.001 −0.252 0.03 −0.183 0.120 −0.289 0.012
Serum albumin 0.139 0.237 0.242 0.038 0.302 0.009 0.315 0.006 0.289 0.012
Cystatin C −0.722  < 0.001 −0.522  < 0.001 −0.546  < 0.001 −0.472  < 0.001 −0.462  < 0.001
  Dt Dp fp
Medulla Cortex Medulla Cortex Medulla
r P r P r P r P r P
eGFR 0.445  < 0.001 −0.091 0.441 0045 0.702 0.007 0.954 0.118 0.316
Serum creatinine −0.525  < 0.001 0.002 0.984 0.026 0.827 −0.208 0.075 −0.157 0.180
ACR −0.01 0.934 −0.053 0.654 0.096 0.414 0.150 0.203 −0.077 0.516
Serum albumin 0.104 0.377 0.102 0.385 0.104 0.377 −0.218 0.062 0.115 0.330
Cystatin C −0.475  < 0.001 0.002 0.988 −0.047 0.690 −0.175 0.136 −0.162 0.168
  1. eGFR estimated glomerular filtration rate, ACR albumin/creatinine ratio, ADC apparent diffusion coefficient, Dt pure diffusion coefficient, Dp perfusion-related diffusion coefficient, fp pseudodiffusion fraction
  2. The unit of T2* is ms; ADC, Dt and Dp value are given as × 10–3mm2/s. The f value is dimensionless