Insights into Imaging

Table 5 Correlation of clinical data and MRI- derived parameters

From: Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging

	T2*				ADC				D_t
	Cortex		Medulla		Cortex		Medulla		Cortex
	r	P	r	P	r	P	r	P	r	P
eGFR	0.824	< 0.001	0.619	< 0.001	0.517	< 0.001	0.482	< 0.001	0.506	< 0.001
Serum creatinine	−0.474	< 0.001	−0.350	0.002	−0.551	< 0.001	−0.475	< 0.001	−0.481	< 0.001
ACR	−0.304	0.008	−0.370	0.001	−0.252	0.03	−0.183	0.120	−0.289	0.012
Serum albumin	0.139	0.237	0.242	0.038	0.302	0.009	0.315	0.006	0.289	0.012
Cystatin C	−0.722	< 0.001	−0.522	< 0.001	−0.546	< 0.001	−0.472	< 0.001	−0.462	< 0.001

	D_t		D_p				f_p
	Medulla		Cortex		Medulla		Cortex		Medulla
	r	P	r	P	r	P	r	P	r	P
eGFR	0.445	< 0.001	−0.091	0.441	0045	0.702	0.007	0.954	0.118	0.316
Serum creatinine	−0.525	< 0.001	0.002	0.984	0.026	0.827	−0.208	0.075	−0.157	0.180
ACR	−0.01	0.934	−0.053	0.654	0.096	0.414	0.150	0.203	−0.077	0.516
Serum albumin	0.104	0.377	0.102	0.385	0.104	0.377	−0.218	0.062	0.115	0.330
Cystatin C	−0.475	< 0.001	0.002	0.988	−0.047	0.690	−0.175	0.136	−0.162	0.168

eGFR estimated glomerular filtration rate, ACR albumin/creatinine ratio, ADC apparent diffusion coefficient, D_t pure diffusion coefficient, D_p perfusion-related diffusion coefficient, f_p pseudodiffusion fraction
The unit of T2* is ms; ADC, D_t and D_p value are given as × 10^–3mm²/s. The f value is dimensionless

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