From: Computed tomography-based multiple body composition parameters predict outcomes in Crohn’s disease
With adverse outcome | Without adverse outcome | p value | |
---|---|---|---|
Demographic data | n = 49 | n = 73 | |
Age (years) | 33.51 ± 14.54 | 31.23 ± 10.04 | 0.308 |
Sex | 0.412 | ||
Male | 40 | 55 | |
Female | 9 | 18 | |
Current smoker | 0.583 | ||
Yes | 7 | 8 | |
No | 42 | 65 | |
Locationa | 0.258 | ||
L1 | 16 | 33 | |
L2 | 14 | 13 | |
L3 | 19 | 27 | |
Disease behavior | 0.001 | ||
Inflammatory | 18 | 50 | |
Complicated | 31 | 23 | |
Duration of disease (years) | 1.70 ± 2.51 | 2.52 ± 3.15 | 0.128 |
Body composition and nutritional parameters | |||
C-reactive protein (mg/L)b | 48.51 ± 39.70 (n = 42) | 39.49 ± 42.41 (n = 65) | 0.274 |
Serum albumin (g/L)b | 34.53 ± 6.52 (n = 49) | 35.55 ± 6.80 (n = 71) | 0.413 |
Erythrocyte sedimentation rate (mm/h)b | 30.93 ± 24.53 (n = 42) | 23.94 ± 21.35 (n = 69) | 0.117 |
BMI (kg/m2) | 17.61 ± 2.41 | 18.85 ± 2.78 | 0.012 |
SAT area (cm2) | 39.18 ± 45.61 | 62.37 ± 51.44 | 0.012 |
VAT area (cm2) | 40.08 ± 42.98 | 57.54 ± 45.59 | 0.036 |
SM area (cm2) | 112.74 ± 22.56 | 122.03 ± 27.26 | 0.051 |
SAT attenuation (HU) | − 65.31 ± 24.83 | − 77.27 ± 24.03 | 0.009 |
VAT attenuation (HU) | − 64.24 ± 13.89 | − 69.72 ± 15.45 | 0.048 |
SM attenuation (HU) | 45.19 ± 8.54 | 46.06 ± 7.36 | 0.546 |
SAI (cm2/m2) | 14.35 ± 17.11 | 22.14 ± 17.99 | 0.018 |
VAI (cm2/m2) | 14.56 ± 16.06 | 20.27 ± 15.67 | 0.053 |
SMI (cm2/m2) | 40.15 ± 6.81 | 42.93 ± 7.86 | 0.046 |
SAIspinal (× 103 cm2/m2) | 1.395 ± 1.739 | 2.097 ± 1.719 | 0.030 |
VAIspinal (× 103 cm2/m2) | 1.477 ± 1.648 | 1.967 ± 1.744 | 0.076 |
SMIspinal (× 103 cm2/m2) | 3.810 ± 7.004 | 4.052 ± 7.745 | 0.081 |
Visceral/subcutaneous fat ratio | 8.06 ± 25.98 | 1.22 ± 0.99 | 0.026 |
Visceral/total fat ratio | 0.58 ± 0.20 | 0.50 ± 0.14 | 0.010 |
Sarcopenia | 0.271 | ||
Yes | 37 | 47 | |
No | 12 | 26 |