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Table 3 Diagnostic performance of each conventional ultrasound and Doppler finding to detect malignant nodules (n = 72)

From: Accuracy of shear wave elastography in characterization of thyroid nodules in children and adolescents

Ultrasound features Sensitivity % (95% CI) Specificity % (95% CI) Accuracy % (95% CI) PPV % (95% CI) NPV % (95% CI)
Hypoechoic echopattern 71.43 (41.9—91.61) 84.48 (72.58—92.65) 81.94 (71.11—90.02) 52.63 (35.88—68.81) 92.45 (84.16—96.58)
Taller than wide 64.29 (35.14—87.24) 67.24 (53.66—78.99) 66.67 (54.57—77.34) 32.14 (21.68—44.76) 88.64 (79.06—94.16)
Halo Absent 85.71 (57.19—98.22) 81.03 (68.59—90.13) 81.94 (71.11—90.02) 52.17 (38.08—65.93) 95.92 (86.62—98.84)
Irregular 57.14 (28.86—82.34) 86.21 (74.62—93.85) 80.56 (69.53—88.64) 50.0 (31.28—68.72) 89.29 (81.86—93.9)
Micro-calcification 78.57 (49.2—96.34) 96.55 (88.09—99.58) 93.06 (84.53—97.71) 84.62 (57.83—95.66) 94.92 (87.24—98.08)
Internal Vascularity 85.71 (57.19—98.22) 89.66 (78.83—96.11) 88.89 (79.28—95.08) 66.67 (47.65—81.46) 96. 30 (87.78—98.85)
Total* 94.2 (73.2–99.8) 69.89 (59.3- 81.85) 74.62 (61.7—85.9) 83.21 (54.5–95.9) 78.9 (63.7–87.6)
  1. PPV, positive predictive value; NPV (negative predictive value
  2. *Total include all above criteria