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Table 6 Associations between the degree of vascularity on color Doppler and clinical /imaging constructs Hemophilia Joint Health Score (HJHS) of the study joint, Pettersson score of the study joint

From: A semiquantitative color Doppler ultrasound scoring system for evaluation of synovitis in joints of patients with blood-induced arthropathy

US operators (data acquisition)   Correlation coefficient r (95% CIs) p value Correlation coefficient r (95% CIs) p value Correlation coefficient r (95% CIs) p value
Semi-quantitative color Doppler US scoring method (synovial vascularity) Quantitative color Doppler US pixel measurement (synovial vascularity) Quantitative gray-scale US measurement (single-layer synovial hypertrophy)
Canada Total Pettersson X-rays scores 0.14 (− 0.25, 0.48) 0.49 0.04 (− 0.34, 0.40) 0.85 0.24 (− 0.15, 0.56) 0.22
China Total Pettersson X-rays scores 0.29 (− 0.06, 0.57) 0.09 0.11 (− 0.25, 0.44) 0.55 0.25 (− 0.10, 0.54) 0.15
Canada Total HJHS scores 0.21 (− 0.20, 0.55) 0.30 0.31 (− 0.09, 0.62) 0.12 0.53 (0.16–0.75) 0.005
China Total HJHS scores 0.32 (− 0.10, 0.63) 0.12 − 0.01. (− 0.41, 0.42) 0.97 0.16 (− 0.26–0.52) 0.46
Canada Presence/absence of swelling (item of HJHS score) 0.32 (− 0.06, 0.61) 0.09 0.38 (0.01, 0.65) 0.04 0.27 (− 0.12–0.57) 0.16
China Presence/absence of swelling − 0.16 (− 0.50, 0.23) 0.41 − 0.20 (− 0.54, 0.21) 0.34 − 0.05 (− 0.41–0.33) 0.81
Canada Duration of swelling (item of HJHS score) 0.10 (− 0.28, 0.45) 0.61 0.23 (− 0.16, 0.54) 0.24 0.06 (− 0.32–0.41) 0.77
China Duration of swelling − 0.01 (− 0.39, 0.36) 0.94 0.12 (− 0.28, 0.48) 0.56 − 0.06 (− 0.42–0.32) 0.77
Canada Flexion loss (item of HJHS score) 0.24 (− 0.15, 0.55) 0.22 0.16 (− 0.22, 0.50) 0.41 0.07 (− 0.31–0.42) 0.72
China Flexion loss 0.38 (− 0.00, 0.65) 0.048 0.40 (0.00, 0.68) 0.04 0.27 (− 0.12–0.58) 0.17
Canada Extension loss (item of HJHS score) 0.34 (− 0.04, 0.62) 0.07 0.25 (− 0.13, 0.56) 0.18 0.39 (0.01–0.65) 0.04
China Extension loss 0.09 (− 0.30, 0.45) 0.65 − 0.16 (− 0.51, 0.24) 0.43 0.10 (− 0.29–0.45) 0.61
Canada Pain (item of HJHS score) 0.23 (− 0.16, 0.54) 0.24 0.13 (− 0.25, 0.47) 0.52 0.34 (− 0.04–0.62) 0.07
China Pain 0.21 (− 0.18, 0.54) 0.28 0.09 (− 0.31, 0.46) 0.68 0.29 (− 0.10–059) 0.14
  1. Bold indicates statistically significant results. p values < 0.05 were considered statistically significant
  2. CI, confidence intervals; R, correlation coefficient