From: RECIST 1.1 and lesion selection: How to deal with ambiguity at baseline?
Category of targets | TL | NTL |
---|---|---|
Factors of inter-reader variability | Size measurement variability for small centimetric lesions (10 mm measurability threshold) Confidence of measuring (e.g., Ill-defined lesions, artefacts) Reproducibility of measurement is not ensured (e.g., position of the lesion, digestive tract lesion) Equivocal malignancy (i.e., benign lesion mimicking malignant lesion, small undetermined lesions) | Several grouped lesions recorded as one NTL Undefined number of NTL Equivocal malignancy (i.e., benign lesion mimicking malignant lesion, small undetermined lesions) |