Fig. 2
From: RECIST 1.1 and lesion selection: How to deal with ambiguity at baseline?
RECIST 1.1 baseline selection accepted variability and errors. TL: Target Lesions are measured by double arrows, NTL: Non-Target Lesions are circled. This patient had a disease limited to the liver. We illustrate 3 different types of baseline lesion selection that can be considered as errors and that deviate from RECIST guidance: a if no NTL have been selected; b if the smallest Target Lesions have been selected instead of the largest; c if only 1 TL has been selected while 2 were measurable. We illustrate 3 different lesion poolings that can be considered as variations from the ideal selection without deviating from the RECIST guidelines: d if NTL lesions are grouped inside an organ; e if different TL are chosen within the largest lesions; f if fewer NTL are selected considering the evaluation as categorial and qualitative even though, preferably, they should all be recorded but practically it is not always possible.