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Table 3 Clinical, biological, radiological characteristics and outcome of PD + and PD- COVID-19 patients

From: Dual-energy CT angiography reveals high prevalence of perfusion defects unrelated to pulmonary embolism in COVID-19 lesions

Characteristics Perfusion defect + (n = 40) Perfusion defect -(n = 27) p value
Age (median, IQR)—yr 64 (55–76) 66 (56–84) 0.494
Male sex—no. (%) 24 (60) 19 (48) 0.444
Time from onset of symptoms to DE-CTPA, days (median, IQR) 14 (7–18) 10 (7–14.5) 0.130
Time from admission to DE-CTPA, days (median, IQR) 1 (0–7) 0 (0–2) 0.045
Disease extent assessed on CT lung images
 < 10%—no. (%) (limited extent) 1 (3) 3 (11) 0.295
 10–50%—no. (%) (regrouping mild and moderate extent) 17 (43) 13 (48) 0.799
 > 50%—no. (%) (regrouping severe and diffuse extent) 22 (55) 11 (41) 0.321
Anticoagulant treatment prior to DE-CTPA
 Preventive dosage—no. (%) 13 (33) 8 (30) 1
 Curative dosage—no. (%) 5 (13) 2 (7) 0.693
Oxygen-support at DE-CTPA
 Invasive ventilation- no. (%) 0 (0) 1 (4) 0.023
 High-flow oxygen (≥ 6 l/min)—no. (%) 14 (35) 7 (26) 0.592
 Low-flow oxygen (< 6 l/min and room air)—no. (%) 26 (65) 19 (70) 0.792
Highest oxygen-support during hospital stay
 Invasive ventilation- no. (%) 9 (23) 3 (11) 0.335
 High-flow oxygen (≥ 6 l/min)—no. (%) 14 (35) 9 (33) 1
 Low-flow oxygen (< 6 l/min and room air)—no. (%) 17 (43) 15 (56) 0.328
Biological characteristics
 D-Dimer level just prior to CTPA—median (IQR) ng/mL 1340 (910–2625) 1590 (1140–2142) 0.340
 Highest level of D-dimer during hospitalization – median (IQR) mg/L 1760 (1173–4085) 2221 (1445–3433) 0.305
 Highest level of CRP during hospitalization – median (IQR) mg/L 146 (75–194) 135 (62–206) 0.944
Prognosis
 Duration of hospital admission (alive patients)- days (median, IQR) 14 (8–23) 9 (4–17) 0.117
 Deaths—no. (%) 3 (8) 6 (22) 0.142