Characteristics | Perfusion defect + (n = 40) | Perfusion defect -(n = 27) | p value |
---|---|---|---|
Age (median, IQR)—yr | 64 (55–76) | 66 (56–84) | 0.494 |
Male sex—no. (%) | 24 (60) | 19 (48) | 0.444 |
Time from onset of symptoms to DE-CTPA, days (median, IQR) | 14 (7–18) | 10 (7–14.5) | 0.130 |
Time from admission to DE-CTPA, days (median, IQR) | 1 (0–7) | 0 (0–2) | 0.045 |
Disease extent assessed on CT lung images | |||
< 10%—no. (%) (limited extent) | 1 (3) | 3 (11) | 0.295 |
10–50%—no. (%) (regrouping mild and moderate extent) | 17 (43) | 13 (48) | 0.799 |
> 50%—no. (%) (regrouping severe and diffuse extent) | 22 (55) | 11 (41) | 0.321 |
Anticoagulant treatment prior to DE-CTPA | |||
Preventive dosage—no. (%) | 13 (33) | 8 (30) | 1 |
Curative dosage—no. (%) | 5 (13) | 2 (7) | 0.693 |
Oxygen-support at DE-CTPA | |||
Invasive ventilation- no. (%) | 0 (0) | 1 (4) | 0.023 |
High-flow oxygen (≥ 6 l/min)—no. (%) | 14 (35) | 7 (26) | 0.592 |
Low-flow oxygen (< 6 l/min and room air)—no. (%) | 26 (65) | 19 (70) | 0.792 |
Highest oxygen-support during hospital stay | |||
Invasive ventilation- no. (%) | 9 (23) | 3 (11) | 0.335 |
High-flow oxygen (≥ 6 l/min)—no. (%) | 14 (35) | 9 (33) | 1 |
Low-flow oxygen (< 6 l/min and room air)—no. (%) | 17 (43) | 15 (56) | 0.328 |
Biological characteristics | |||
D-Dimer level just prior to CTPA—median (IQR) ng/mL | 1340 (910–2625) | 1590 (1140–2142) | 0.340 |
Highest level of D-dimer during hospitalization – median (IQR) mg/L | 1760 (1173–4085) | 2221 (1445–3433) | 0.305 |
Highest level of CRP during hospitalization – median (IQR) mg/L | 146 (75–194) | 135 (62–206) | 0.944 |
Prognosis | |||
Duration of hospital admission (alive patients)- days (median, IQR) | 14 (8–23) | 9 (4–17) | 0.117 |
Deaths—no. (%) | 3 (8) | 6 (22) | 0.142 |