Fig. 11

Example of preoperative chemotherapy-induced fibrosis in a 64-year-old male patient with non-otherwise specified (NOS) adenocarcinoma of the colon. Contrast-enhanced fat-saturated gradient recall echo T1-weighted images on delayed phase images before (a) and after (b) treatment. Before treatment, the liver metastasis (arrow) shows progressive peripheral enhancement consistent with the presence of fibrous stroma. After treatment, a shrinkage of the lesion and the appearance of a focal capsular retraction (arrow) is observed. The pathological specimen (c) shows a 20 mm metastasis of a NOS adenocarcinoma containing a large amount of fibrosis with liver capsule retraction (arrow)