Fig. 27

Syringomatous tumor of the nipple. A 47-year-old woman with retraction and hardening of the left nipple. a Mammogram shows retraction of the left nipple and asymmetric retroareolar density. b On ultrasound, the lesion is solid and hypoechogenic with ill-defined borders and increased peripheral color-Doppler signal. c Contrast-enhanced coronal T1-weighted MRI (subtracted image obtained 120 s after contrast injection) shows mass-type uptake with pronounced early enhancement in a lesion with hazy borders that retracts the nipple-areolar complex. d Hematoxylin-eosin stain (× 4) shows a proliferation of elongated glandular structures like strings of cells in the dermis, with the formation of keratin cysts (star)