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Fig. 3 | Insights into Imaging

Fig. 3

From: Imaging indications and findings in evaluation of lung transplant graft dysfunction and rejection

Fig. 3

Transbronchial biopsy findings in acute cellular rejection following lung transplantation. The vascular component of acute cellular rejection (a) is characterized by a lymphocyte-rich inflammatory infiltrate involving and surrounding small blood vessels within lung parenchyma. The Movat pentachrome stain (b) helps to highlight elastic layers in the blood vessel, demonstrating that inflammatory cells breach the elastic layers (black wavy lines) and involve the vascular intima (arrow). Airways involved by acute cellular rejection (c) show inflammation (long arrow). In more advanced examples, there is epithelial damage, manifested by sloughing of epithelial cells into the airway lumen (short arrow)

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