Fig. 10
CEUS LI-RADS M (probably or definitely malignant but not HCC specific) nodule. Cholangiocarcinoma in a 87-year-old man with virus B-related cirrhosis. Baseline US image shows a markedly heterogeneous lesion sized 8.5 cm in the segment VI (a) (arrows). No vascular signal is detectable at color-Doppler (b). At CEUS (c), the nodule shows rim enhancement surrounding a constantly avascular area (arrows)