Mapping the ischemic penumbra and predicting stroke progression in acute ischemic stroke: the overlooked role of susceptibility weighted imaging

Insights into Imaging

Table 2 Patients’ demographic data and imaging findings

		NIG group	IG group	p value	Sig.
		No. = 14	No. = 6	p value	Sig.
Age (years)	Median (IQR)	64 ( 52–67.75)	60 (51–69.5)	0.934	NS^*
Age (years)	Range	36–73	45–74	0.934	NS^*
Gender	Females	4 (28.6%)	4 (66.7%)	0.111	NS^**
Gender	Males	10 (71.4%)	2 (33.3%)	0.111	NS^**
Infarct side	Right	7 (50.0%)	4 (66.7%)	0.492	NS^**
Infarct side	Left	7 (50.0%)	2 (33.3%)	0.492	NS^**
Mismatch	SWI aspects > initial DWI aspects (negative mismatch)	4 (28.6%)	0 (0.0%)
	SWI aspects < initial DWI aspects (positive mismatch)	4(28.6%)	6 (100%)	0.014	S^**
	No SWI–DWI mismatch	6 (42.9%)	0 (0.0%)
Initial DWI ASPECTS	Median(IQR)	7 (4.75–8)	7.5 (6–8)	0.356	NS^*
Initial DWI ASPECTS	Range	1–9	6–9	0.356	NS^*
SWI aspects	Median(IQR)	7 (5–8)	3.5 (2.5–4.5)	0.004	HS^*
SWI aspects	Range	4–9	1–6	0.004	HS^*
FUP ASPECTS	Median(IQR)	7 (4.75–8)	5.5 (3–6.5)	0.261	NS^*
FUP ASPECTS	Range	1–9	3–8	0.261	NS^*
DWI/SWI mismatch score	Median (IQR) Range	0 (− 1.25–2) − 6–2	3.5 (3–4.5) 3–6	0	HS^*
Infarct growth score	Median (IQR) Range	0 (0) 0	2 (1.75–3) 1–3	0	HS^*
Time to MRI (h)	Median (IQR) Range	14 (7.875–20.125) 6–24	12.5 (7.75–20.5) 7–22	0.869	NS^*
Follow-up time (days)	Median (IQR)	7 (5–9.25)	8.5 (5–14)	0.498	NS^*
Follow-up time (days)	Range	5–15	5–14	0.498	NS^*

ASPECTS Alberta Stroke Program Early CT Score, DWI diffusion-weighted imaging, FUP follow-up, HS highly significant, IG infarct growth, IQR- interquartile range, NIG non-infarct growth, NS non-significant, S significant, SWI susceptibility-weighted imaging
^*Wilcoxon rank-sum test
^**Chi-squared test