Table 2 Diagnostic accuracy measures in non-contrast-enhanced MRI techniques and contrast-enhanced techniques in multiple sclerosis
Clinical question | Diagnostic performance non-CE | Diagnostic performance CE gold standard | Author (year) |
|---|---|---|---|
Predict contrast enhancement in multiple sclerosis | AUC 0.83 (95% CI 0.80–0.87) non-enhanced conv MRI and logistic regression model fitting | CE T1 reference standard | Shinohara et al. (2012) |
Predict contrast enhancement in multiple sclerosis | AUC 0.72 T2 burden of disease | CE T1 reference standard | Barkhof et al. (2005) |
Predict contrast enhancement in multiple sclerosis | AUC 0.93 (95% CI 0.87–0.99) T2W, SDC, QSM | CE T1 reference standard | Gupta et al. (2018) |
Predict contrast enhancement in multiple sclerosis | T2-weighted texture parameters 86% sensitivity, 84% specificity | CE T1 reference standard | Michoux et al. (2015) |