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Insights into Imaging
Fig. 10 | Insights into Imaging

Fig. 10

From: Diffuse smoking-related lung diseases: insights from a radiologic-pathologic correlation

Fig. 10

Pulmonary Langerhans cell histiocytosis in a 40-year-old man. a Axial CT image shows upper lobe predominance of nodules and cysts of varying wall thickness and irregular margins. Arrow depicts a stellate cellular nodule. b Transthoracic lung biopsy of the nodule highlighted in a shows a nodular aggregate of cells (lymphocytes, eosinophils, plasma cells, and Langerhans cells) centered in bronchioles (arrow) and extending to the interstitium (H&E, × 200). c CD1a immunostaining highlights the Langerhans cells (CD1a, × 100)

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