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Table 1 Interpretation of tumor diffusion-weighted images

From: How clinical imaging can assess cancer biology

Signal intensity on high b-value images (b800–b1000)

Relative value on apparent diffusion coefficient (ADC) maps

Signal intensity on T2-weighted images

Interpretation

High

Low

Intermediate

Generally, high cellularity tumor

Coagulative necrosis

Abscess

Rarely high protein content

High

High

High

T2-shine through

(often proteinaceous fluid)

Low

Low

Low

Fibrous tissue with low water content +/- viable tumor

Low

High

High

Fluid

Liquefactive necrosis

Lower cellularity/grade tumor

Glandular tissue

Low

High

High

Vasogenic edema (T2-wash out)

Low

Low

Variable

Hemorrhagic content (T2-black out)