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Table 2 Specific CT pattern with alloimmune complications

From: Radiological findings of complications after lung transplantation

Alloimmune responses

Acute rejection

BOS

RAS

AFOP

Time of occurrence

1–12 weeks

6–18 months

6–18 months

6–18 months

Clinical keys

Acute dyspnea

Chronic dyspnea, cough

Decrease in FEV1 and FEV1/FVC ratio

Chronic dyspnea

Decrease in FEV1 and TLC

Acute dyspnea

Decrease in FEV1

CT signs

Ground-glass opacities

Interlobular septal thickening

Pleural effusions

Volume loss

“Obstructive phenotype”

Bronchiectasis

Bronchial thickening

Expiratory air-trapping

“Restrictive phenotype”

Bronchiectasis

Peripheral consolidations or ground-glass opacity

Subpleural thickening

Architectural distortion

Upper lobe predominance

Volume loss

Inter-/intralobular septal thickening

Peripheral ground-glass opacity and consolidations

  1. AFOP: acute fibrinous organizing pneumonia; BOS: bronchiolitis obliterans syndrome; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; RAS: restrictive allograft syndrome; TLC: total lung capacity