Fig. 5

Diagnostic criteria: suspicious internal enhancement patterns. Heterogeneous enhancement may be associated with breast cancer and applies to mass and non-mass lesions (A, upper and lower row, respectively). Specific for malignancy is a centripetal or rim-like enhancement (B). In particular, a broad heterogeneous rim, regularly associated with a delayed enhancement of the central lesion parts, is highly suggestive of breast cancer (B, upper row). However, a thin, rather subtle and homogeneous rim enhancement with absent enhancement of the lesion centre hints at inflammatory conditions, such as cysts, liponecrosis, and abscess (B, upper row, left upper lesion). In non-mass lesions, rim enhancement may appear in a multiple and clustered manner (B, lower row) and is referred to as “clustered ring enhancement” in the BI-RADS lexicon