Table 1 Likelihood and odds ratios for malignancy regarding morphological features in solitary pulmonary nodules
From: Evaluation of the solitary pulmonary nodule: size matters, but do not ignore the power of morphology
| Â | Gurney et al. Radiology 1993 [3] | Swensen et al. Arch Intern Med 1997 [8] | Li et al. World J Surg 2012 [11] | McWilliams et al. N Engl J Med 2013 [12] | Soardi et al. Eur Radiol 2015 [13] |
|---|---|---|---|---|---|
Population | Non-screen | Non-screen | Non-screen | Screen-detected | Non-screen |
Number of nodules studied | Literature review | 629 | 371 | 12,029 | 343 |
Morphological features | |||||
 Subsolid |  |  |  | No spiculation Ground glass: OR 0.74 (CI 0.40–1.35) Part-solid: OR 1.40 (CI 0.72–2.74) With Spiculation Ground glass: OR 0.88 (CI 0.48–1.62) Part-solid: OR 1.46 (CI 0.74–2.88) |  |
 Smooth | LHR 0.30 (CI 0.20–0.41) |  | OR 0.245 (CI 0.133–0.451) |  | LHR 0.293 (smooth, elliptical, polygonal) |
 Lobulated | LHR 0.74 (CI 0.64–0.84) | OR 2.520 (CI 1.423–4.433) |  |  | LHR 0.735 (minimally lobulated) LHR 1.888 (deeply lobulated) |
 Spiculated | LHR 5.54 (CI 5.46–5.63) | OR 5.789 (CI 3.332–10.057) | OR 2.088 (CI 1.055–4.135) | OR 2.17 (CI 1.16–4.05) | LHR 7.884 |
 Calcification | LHR 0.01 (CI 0–0.03) |  | OR 0.199 (CI 0.067–0.587) |  |  |
 Cavitation |  | OR 3.05 (CI 1.078–8.646) |  |  |  |