Table 1 Indications for imaging-guided chest biopsy

1. A new or enlarging solitary nodule or mass

2. Multiple nodules in a patient without known neoplastic disease or in prolonged remission

3. Focal parechymal infiltrates in which an infectious organism cannot be isolated

4. Diagnosis of hilar masses following negative broncoscopy

5. Undiagnosed mediastinal mass.

6. Bipopsy or re-biopsy of malignancy for targeted therapy.