Fig. 3

A. Global cortical atrophy (GCA) rating on MR. Interpretation key. Numbers equal the corresponding image in the supplementary PDF file. a/1) GCA0. b/17) GCA0-1. c/7) GCA0-1. Note the powerful widening of the lateral ventricles and especially the frontal horns. Normal pressure hydrocephalus? d/8) GCA0-1 with bifrontal GCA1. Note the widening of the posterior horns of the lateral ventricles. e/14) Bifrontal GCA1 and biparietal GCA0. Note the wide lateral ventricles. f/11) GCA0. Some atrophy of one or two of the temporal gyri and widening of the Sylvian fissure, especially on the left side, GCA2. g/2) GCA1 in the parietal lobe. GCA1 and 2 in the frontal lobes. h/4) GCA1. GCA2 in the left side at the junction between the frontal and parietal lobes. i/5) GCA1-2, but mostly GCA2. j/16) GCA1 going towards GCA2. k/9) GCA1. Maybe atrophy in the frontal midsagital region with mild atrophy of the anterior cingulate gyri, GCA2? l/6) GCA2 m/13) BifrontalGCA1 and biparietal GCA2. n/20) GCA2, more atrophy left parietal. o/18) Bifrontal GCA2 and biparietal GCA1. p/19) GCA0 except for anterior gyri in both temporal lobes, GCA 2–3 left temporal and GCA1-2 right temporal. q/3) GCA2 in the left frontal lobe and GCA2-3 in the right. A few gyri with GCA3.GCA0-1 in the parietal lobes. Note the widening of the frontal horns of lateral ventricles and the atrophy of the anterior cingulate gyri. r/10) BifrontalGCA 2–3 and biparietal GCA0-1. Note atrophy of the cingulate gyrus and wide frontal horns. s/12) GCA3 in the temporal lobe on the left side. GCA1 on the right side and GCA2 in the cerebellum. t/15) GCA2 and maybe GCA3 in the Sylvian fissure. Biparietal GCA1. B. Global cortical atrophy (GCA) rating on CT. Interpretation key. Numbers equal the corresponding image in the supplementary PDF file. a/1) GCA0 b/17) GCA0-1. c/5) GCA1. d/2) GCA1. e/8) GCA1. f/10) GCA1. g/18) GCA1 in the right hemisphere and GCA2 in left hemisphere. h/9) GCA1 in the more frontal part of the frontal lobes. GCA2 in general. i/19) In-between GCA1-2, but closer to GCA2. j/13) In-between GCA1-2, GCA2 bifrontal. Note the cavum septi pellucidi. k/3) Bifrontal GCA2 and biparietal GCA1.Note the wide frontal horns. l/6) Bifrontal GCA2, biparietal GCA1. m/7) GCA2 fronto-parietal. n/20) GCA2. o/16) GCA2, frontal lobe left.GCA1 in the right frontal lobe and GCA0 in the parietal lobes. Note the atrophy in the anterior cingulate gyri. p/11) Biparietal GCA2 and bifrontal GCA1. q/14) Another image of the same patient, GCA2. r/12) Note the side difference. GCA2 along the left hemisphere, GCA1 on the right side. s/15) GCA2 in supraorbital part of the frontal lobes and in the anterior part of the temporal lobes.GCA0 in the more posterior part of the temporal lobes. t/4) GCA3 in a few parietal gyri on the right side. Bifrontal GCA2 and GCA1 left parietal