Fig. 8
From: MRI in multiple myeloma: a pictorial review of diagnostic and post-treatment findings
MR images of a patient with symptomatic multiple myeloma, 30Â % plasma cells on bone marrow biopsy. a T1-weighted and T2-weighted STIR coronal images of the body and b T1-weighted and fat-suppressed T2-weighted images of the thoracolumbar spine displaying a significant decrease of signal intensity on T1-weighted images with a corresponding increased signal intensity on T2-weighted images, diffuse infiltration pattern, and also remark the additional focal lesions in the vertebral bodies of T2 and T9 (arrows). c Increased signal intensity on DWI b1000 images, due to a decrease in bone marrow fat cells, increased cellularity, and water amount with corresponding increase in water diffusivity. d Increased angiogenesis, perfusion and vascular permeability displayed in a time-intensity curve type 4, with early wash-out of the contrast medium