Fig. 4
From: MRI in multiple myeloma: a pictorial review of diagnostic and post-treatment findings
Five types of time-intensity curves (TICs) have been described. Type 1 (blue) demonstrates no enhancement, whereas type 2 (green) illustrates a slow sustained enhancement. Type 3 (purple), 4 (orange) and 5 (red) are characterized by a steep and fast first pass enhancement; in type 3 this is followed by a sustained late enhancement; in type 4 this is followed by a wash-out of contrast medium caused by a small interstitial space. The steep wash-in of type 5 is followed by a stable late enhancement