Fig. 2
From: Spectrum of early lung cancer presentation in low-dose screening CT: a pictorial review
Increased attenuation of a small lung adenocarcinoma over 3 years in a 62-year-old man. (a) Low-dose CT image show a 5-mm non-solid nodule of the upper left lobe (arrow). (b) Follow-up CT obtained 1 year later show a minimum increment of axial diameter and a slight increase of nodule attenuation. (c) Two years later the progression to a part-solid nodule is obvious. The development of a central solid component (arrowhead) within the nodule can be observed. An increase in pulmonary nodule attenuation at LCDT follow-up, the development or increment of a solid component within the pulmonary nodule should raise suspicions of malignancy, even if the nodule size is stable. Typically, this appearance is suggestive of a peripheral lung adenocarcinoma