Fig. 12
From: Spectrum of early lung cancer presentation in low-dose screening CT: a pictorial review
Lung cancer arising within a pre-existing fibrotic lung disease. (a) Low-dose CT demonstrates a bilateral subpleural reticular pattern and a ground-glass opacity, with a subpleural curvilinear opacity in the right lower lobe (arrowheads). (b) Low-dose CT scan obtained 1 year later confirmed the fibrotic disease with an increased density of the subpleural opacity in the right lower lobe (arrowheads), interpreted as a progression of the fibrosing pattern. (c) At follow-up CT performed 1 year later, there is a remarkable increase of subpleural opacity in the right lobe with the development of a 32-mm mass, resulting in lung adenocarcinoma (arrow)