Fig. 2
From: Systemic treatment in breast cancer: a primer for radiologists
58-year-old woman with estrogen receptor-positive metastatic breast cancer treated with trastuzumab. a Axial contrast-enhanced CT image of the abdomen demonstrates a subcentimeter hypodense lesion in the liver (arrow) and ascites. b Follow-up scan after 3 months of treatment shows increase in the size of the liver metastasis with concurrent decrease in the ascites. Patient continued therapy due to decrease in tumour markers. c Repeat scan 2 months later shows decreased size of liver metastasis. The transient increase in the size of the metastasis on the interim scan (b) was due to decreased enhancement of the lesion suggestive of pseudoprogression