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Insights into Imaging
Fig. 10 | Insights into Imaging

Fig. 10

From: Beyond PET/CT in Hodgkin lymphoma: a comprehensive review of the role of imaging at initial presentation, during follow-up and for assessment of treatment-related complications

Fig. 10

Second malignancies in patients with HL. a A 40-year-old female with a history of nodular sclerosing HL at the age of 15 treated with chemotherapy and upper mantle radiation. Axial contrast-enhanced lung window CT image shows a soft tissue mass within the right paramediastinal radiation field. Pathology was suggestive of adenocarcinoma of the lung. b A 24-year-old female presenting with upper abdominal pain and fullness with a prior history of HL at the age of 13 treated with splenectomy and radiation. Axial non-enhanced CT image of the upper abdomen shows a soft tissue mass lesion in the left upper abdomen (arrow). Pathology was suggestive of mesothelioma. c A 48-year-old female with a history of nodular sclerosing HL at the age of 15 treated with chemotherapy, mantle and pelvic radiation. Transverse greyscale ultrasound image shows a solid nodule in the right lobe of the thyroid (arrow). Fine-needle aspiration cytology from the nodule was suggestive of papillary thyroid carcinoma. d A 56-year-old female presenting with shortness of breath, intermittent cough and weight loss with a prior history of HL treated with radiation 40 years ago. Axial contrast-enhanced CT image shows a large heterogeneously enhancing anterior mediastinal mass (arrow). Pathology was suggestive of radiation-induced sarcoma

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