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Table 1 List of clinical and imaging features used in the differential diagnosis between enchondroma and chondrosarcoma

From: The role of magnetic resonance imaging in the evaluation of bone tumours and tumour-like lesions

Enchondroma

Chondrosarcoma

More common in extremities

More common in the axial skeleton

No pain (only if associated with fracture)

Can cause pain

No periostitis

Can have associated periostitis

No growth beyond skeletal maturity

Rapid growth, regardless of the skeletal maturity

No soft tissue component

Associated focal cortical thickening

Absence of bone oedema

Different patterns of signal intensity

Size usually ≤4 cm

Bone destruction

 

Loss of calcifications on follow-up

 

Soft tissue component

 

Bone marrow oedema

 

Size usually >4 cm