Table 3 Inclusion and exclusion criteria for TAVR

Inclusion criteria:

 Critical aortic stenosis (with mean aortic valve area of <0.8 cm²)

 Multiple comorbidities with 1-year mortality rate exceeding 20 %

 Poor outcome with medical management

 Non-surgical candidates with TAVR representing the only suitable alternative

 Native aortic annular size appropriate for currently available THV size criteria

Exclusion criteria: unsuitable native anatomy

 Lack of appropriate access to implant the device

 Sinuses of Valsalva unable to accommodate prosthetic valve

 Native aortic annular size inappropriate for currently available THV size criteria