Fig. 14
From: Radiolucent lesions of the mandible: a pattern-based approach to diagnosis
SCC with mandibular invasion. Precise pre-operative assessment with MRI and PET/CT. a OPT. Poorly defined bony destruction (arrow) of the edentulous mandible. b Contrast-enhanced axial CT. Aggressive soft-tissue lesion (arrow) with secondary bone invasion. c Sagittal oblique PET/CT image. High metabolism of the tumour (black asterisk, SUVmean = 18, SUVmax = 22) and of two metastatic level I lymph nodes (arrows, SUVmean = 10, SUVmax = 15). d T2-weighted axial image. Tumour (asterisk) with marrow invasion and extensive infiltration of the floor of the mouth (dashed arrow). Note two metastatic level I lymph nodes (arrows). e The b 1,000 and f ADC map show restricted diffusion within the tumour (circle, ADC = 0.98 × 10−3 mm2/s). Variable ADC values within the metastatic lymph nodes due to the presence of necrosis (arrows in f). g Sagittal histological whole-organ slice of the resected specimen. Tumour (dashed black line) invading the mandible (black arrows) and the muscles (asterisk) of the floor of the mouth. The histological slice has the same orientation as (c)