Fig. 10
From: Radiolucent lesions of the mandible: a pattern-based approach to diagnosis
Biphosphonate osteonecrosis. a OPT; b 3D reconstruction anteo-lateral view. Contrast-enhanced axial CT image with bone window settings (c) and soft tissue settings (d). Poorly defined osteolytic lesion of the left mandibular body (thick white arrows) with partly sclerotic margins (thin arrows in a) and large osseous defect (red arrows in b). Bone sequestra (dashed arrows). Associated subperiosteal phlegmon and myositis of the platysma (open arrows). e Histology (haematoxylin-eosin stain, original magnification 20×): necrotic bone (large asterisk) with inflammatory infiltration of the fatty marrow (small asterisks). Gingival mucosa (arrows)