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Table 1 Classification of brain stones according to location and aetiopathology

From: Brain stones revisited—between a rock and a hard place

Location/aetiology

Examples

Extra-axial

Meningiomas, dural osteomas, calcifying tumours (e.g., craniopharyngiomas), calcifying pseudoneoplasms of the neuraxis (CAPNON), exaggerated physiological calcifications

Intra-axial

 Neoplastic

Oligodendrogliomas, medulloblastoma, germ cell tumours, primitive neuroectodermal tumours (PNET), dysembryonic neuroectodermal tumours (DNET), gangliomas, pilocytic astrocytomas

 Vascular

Cavernous malformations, arteriovenous malformations, dystrophic calcification in chronic infarction, chronic vasculitis, aneurysms

 Infectious

TORCH (toxoplasmosis, rubella, cytomegalovirus, herpes simplex), tuberculosis, parasitic infections (e.g. neurocyticercosis, cerebral hydatid cyst disease)

 Congenital

Sturge-Weber syndrome, tuberous sclerosis, lipomas, neurofibromatosis

 Endocrine/metabolic

Fahr’s syndrome, hypoparathyroidism, pseudohypoparathyroidism, hyperparathyroidism