Skip to main content

Table 1 Comparison of MR findings among malignant lymphoma, autoimmune pancreatitis and pancreatic adenocarcinoma

From: MR features of primary and secondary malignant lymphoma of the pancreas: a pictorial review

Finding

Lymphoma

AIP

PAC

Speckled hyperintensity on FST1WIa

None

Sometimes

Rare

Target appearance on T2WIb

Rare

Rare

Frequent

Duct-penetrating sign (in focal lesions)

Rare

Sometimes

Rare

Marked upstream MPD dilatation

Sometimes

Rare

Frequent

Speckled enhancement on PP DCE-MRIc

None

Frequent

Rare

Homogeneous enhancement on EP DCE-MRI

Sometimes

Common

Rare

Target appearance on PP or EP DCE-MRIb

Rare

Rare

Common

Without delayed enhancement

Frequent*

Rare

Rare

Diffuse enlargement (sausage appearance)

Sometimes

Sometimes

Rare

Capsule-like rim (in diffuse lesions)

Rare

Frequent

None

Multi-focal lesions

Sometimes

Sometimes

None

Vascular involvement without obstruction

Sometimes

Sometimes

Rare

Lymphadenopathy below the level of the left renal vein

Sometimes

Rare

Rare

Other organ involvement

None (primary)/common (secondary)

Common

Sometimes (metastasis)

  1. AIP autoimmune pancreatitis, PAC pancreatic adenocarcinoma, FST1WI fat-suppressed T1-weighted image, T2WI T2-weighted image, MPD main pancreatic duct, DCE-MRI dynamic contrast-enhanced magnetic resonance imaging, PP pancreatic phase, EP equilibrium phase
  2. aSpeckled hyperintensity is defined as a hypointense or isointense lesion including speckled or dotted hyperintense areas
  3. bTarget sign is defined as a hyperintense lesion surrounding a more hyperintense focal area on fat-suppressed T2WI or a hypointense to hyperintense lesion surrounding a more hypointense area on DCE-MRI
  4. cSpeckled enhancement is defined as hypointense or isointense areas including speckled or dotted enhanced areas on DCE-MRI
  5. *Specific finding in comparison between malignant lymphoma and AIP
  6. Specific finding in comparison between malignant lymphoma and PAC
  7. Specific finding in comparison between AIP and PAC