The role of magnetic resonance imaging in assessing residual disease and pathologic complete response in breast cancer patients receiving neoadjuvant chemotherapy: a systematic review

Insights into Imaging

Table 4 Diagnostic accuracies of MRI for predicting pathologic complete response

Author	Sensitivity (%)	Specificity (%)	PPV (%	NPV (%)	Accuracy (%)	Prevalence
Rieber et al.	42	89	73	71	72	0.21
Schott et al.	25	97	50	94	89	0.10
Bhattacharyya et al.	80	89	56	96	NA	0.13
Moon et al.	38	96	NA	NA	NA	0.15
De Los Santos et al.	92	50	72	80	NA	0.40
Fangberget et al.	38	96	NA	NA	NA	0.37
Park et al.	100^a	70^a	47^a	100^a	77^a	0.21
Shin et al.	77	70	NA	NA	NA	0.33
	100^a	91^a	NA^a	NA^a	NA^a
	53^b	70^b	NA^b	NA^b	NA^b

PPV positive predictive value, NPV negative predictive value, NA not available, tCho total choline-containing compounds
The results are presented for dynamic, contrast-enhanced MRI, with the exception of: ^adiffusion-weighted imaging and ^bMR spectroscopy parameters