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Fig. 9 | Insights into Imaging

Fig. 9

From: The complex of myxomas, spotty skin pigmentation and endocrine overactivity (Carney complex): imaging findings with clinical and pathological correlation

Fig. 9

a Picture from the adrenal gland from a patient with PPNAD with characteristic preservation of the normal gland shape. Multiple nodules (red arrows) throughout the cortex, that barely distort the outline of the gland, give it the characteristic picture of “beads on a string”. b Another magnification (2.5×) of the same adrenal gland showing multiple nodules and diffuse hyperplasia (N nodule, H hyperplasia). c Another view (2.5× magnification) of the adrenal gland showing how nodules can coalesce in this view there is little hyperplastic cortex and even atrophy. The preservation of the medulla is also shown. d One of the nodules at 20× magnification (red box from picture c) showing cells filled with lipids (black arrows), characteristic of the steroidogenesis, and lipofuscin (red arrows)

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