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Table 3 Diagnostic performance of 3D SPACE and routine MR imaging protocol in the detection of cartilage lesions for all readers

From: Diagnostic performance of 3D SPACE for comprehensive knee joint assessment at 3 T

 

Reader 1

Reader 2

Reader 3

 

2D

3D

p-value

2D

3D

p-value

Complete exam

Overall cartilage

       

Sensitivity

71 [48–89] (15/21)

76 [53–92] (16/21)

1,000

81 [58–95] (17/21)

81 [58–95] (17/21)

1,000

81 [58–95] (17/21)

Specificity

94 [90–96] (205/219)

95 [91–97] (208/219)

0.6072

99 [96–100] 216/219

95 [92–98] (209/219)

0.0923

99 [96–100] (216/219)

Accuracy

92 [87–95] (220/240)

93 [89–96] (224/240)

0.4807

97 [94–99] (233/240)

94 [90–97] (226/240)

0.1185

97 [94–99] (233/240)

Tibiofemoral compartment

       

Sensitivity

64 [31–89] (7/11)

64 [31–89] (7/11)

1,000

73 [39–94] (8/11)

73 [39–94] (8/11)

1,000

73 [43–90] (8/11)

Specificity

95 [91–98] (142/149)

97 [92–99] (144/149)

0.7539

98 [94–100] (146/149)

98 [94–100] (146/149)

1,000

98 [94–99] (146/149)

Accuracy

93 [88–97] (149/160)

94 [90–97] (151/160)

0.7744

96 [92–100] (154/160)

96 [92–99] (154/160)

1,000

96 [92–98] (154/160)

Patellofemoral compartment

       

Sensitivity

80 [44–97] (8/10)

90 [55–100] (9/10)

1,000

90 [55–100] (9/10)

90 [55–100] (9/10)

1,000

90 [60–98] (9/10)

Specificity

90 [80–96] (63/70)

91 [82–97] (64/70)

1,000

100 [92–100] (70/70)

90 [80–96] (63/70)

0.0156*

100 [95–100] (70/70)

Accuracy

89 [80–95] (71/80)

91 [83–96] (73/80)

0.6875

99 [93–100] (79/80)

90 [81–96] (72/80)

0.0156*

99 [93–100] (79/80)

  1. Sensitivity, specificity and accuracy data are percentages with number/total in parentheses. Data in brackets are lower and upper bounds of 95 % confidence intervals
  2. *P-value < 0.05 indicates a significant difference