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Table 2 Differences in epidemiology and morphology on MRCP of cystic pancreatic tumours

From: Magnetic resonance cholangiopancreatography: the ABC of MRCP

 

Serous cystadenoma

Mucinous cystic neoplasms

Intraductal mucinous neoplasm (IPMN)

Demographics

Typically older women >60 years

Typically younger women 30-50 years

Peak age 6th decade, no gender bias

Site of tumour

Anywhere in the pancreas, especially the head

75% in body/tail

Side branch type: usually pancreatic head/uncinate process, less frequently in the tail; tumour communicates with the main pancreatic duct

Main duct type: segmental or diffuse involvement of the main pancreatic duct

Morphology

>6 cysts (<2 cm each), thin septations, central scar (calcification), does not communicate with the pancreatic duct

Cysts >2 cm, unilocular or multilocular, does not communicate with the pancreatic duct

Side branch type: macrocystic or microcystic appearances

  

Features of malignancy on MR denoted by thick septations, soft tissue nodules, and/or pancreatic duct dilatation

Main duct type: diffuse duct dilatation due to gross mucin production, micropapillary studding, pancreatic atrophy

Average size

5 cm

6-10 cm

Larger size with malignant tumours

Signal characteristics

Fluid signal

High signal intensity on T1 and T2 (mucin/blood)

High signal intensity on T1 (mucin), intermediate signal intensity on T2

Comments

Usually benign

Malignant in 50%

Side branch type: usually associated with benign adenomas

Main duct type: malignant in 40%