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Fig. 5 | Insights into Imaging

Fig. 5

From: Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases

Fig. 5

In vivo TSPO imaging by PET. PET imaging of microglial cells in vivo involves utilising ligands labelled with 11C or 18F radioisotopes that bind translocator protein (TSPO) expressed on the outer mitochondrial membrane in microglia. The radioisotope undergoes positron emission decay underlying the principle of PET imaging

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