Local spread | •Uterus and broad ligament (via the fallopian tube); |
•Direct invasion of the rectum, colon, bladder and pelvic side wall | |
Lymph node spread | •Via lymphatics travelling along with the ovarian vessels to terminate in common iliac and para-aortic nodes; |
•Via the broad ligament to terminate in the internal iliac and obturator nodes; | |
•Via the round ligament to terminate in the external iliac and inguinal nodes | |
Trans-coelomic spread | •Common sites: undersurface of the diaphragm, liver surface, pouch of Douglas, omentum, serosal bowel surfaces |
Haematogenous spread | •This occurs late during the disease; |
•Liver > lungs, kidney, bone | |
Note | •Ascites arise from increased production from tumour surfaces and/or occlusion of retroperitoneal lymph nodes |