Local spread | •Invasion through the bowel wall into the peri-colonic fat and adjacent structures |
Lymph node spread | •Follows the vascular distribution of vessels in mesocolon; |
•Ascending mesocolon: nodes along the ileocolic vessels and right colic vessel; | |
•Transverse mesocolon: nodes along the middle colic vessels; | |
•Sigmoid and descending mesocolon: nodes along the inferior mesenteric vein; | |
•Regional lymph nodes for rectal cancers include: mesorectal, sigmoid mesenteric, inferior mesenteric, lateral sacral, presacral, internal iliac, sacral promontory, superior rectal, middle rectal and inferior rectal | |
Haematogenous spread | •Liver (via the portal vein) > lung, adrenal glands, bones |
Notes | •In rectal cancers that have perforated the peritoneum, transcoelomic spread favours the lower right small bowel mesentery and the pouch of Douglas |