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Table 5 Univariate and multivariate predictors of total cardiac events in diabetics and non-diabetics

From: Prognostic value of CT coronary angiography in diabetic and non-diabetic subjects with suspected CAD: importance of presenting symptoms

 

Diabetics (n = 210)

Non-diabetics (n = 203)

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

HR (95% CI)

p Value

HR (95% CI)

p Value

HR (95% CI)

p Value

HR (95% CI)

p Value

Clinical characteristics

Age (>65 years)

3.80 (1.94–7.44)

<0.001

2.22 (1.09–4.51)

0.03

1.97 (0.81–4.80)

0.14

  

Male gender

0.89 (0.46–1.73)

0.74

  

3.41 (1.0–11.58)

0.05

  

Hypertension

2.53 (1.06–6.03)

0.04

  

1.39 (0.54–3.59)

0.50

  

Family history

1.54 (0.80–2.95)

0.19

  

1.76 (0.72–4.28)

0.22

  

Smoking

2.03 (1.07–3.87)

0.03

  

1.87 (0.78–4.49)

0.16

  

Hypercholesterolaemia

1.79 (0.93–3.45)

0.08

  

1.85 (0.74–4.61)

0.19

  

Obesity

0.91 (0.47–1.79)

0.79

  

0.45 (0.10–1.91)

0.28

  

Symptoms

Asymptomatic

0.34 (0.14–0.81)

0.016

  

0.28 (0.06–1.19)

0.09

  

Typical angina pectoris

3.29 (1.63–6.65)

<0.001

2.91 (1.34-6.31)

0.007

9.47 (3.93–22.8)

<0.0001

2.75 (1.06–7.1)

0.03

Atypical angina pectoris

0.63 (0.30–1.29)

0.21

  

0.39 (0.13–1.17)

0.09

  

Dyspnoea

2.05 (0.99–4.24)

0.05

3.8 (1.7–8.51)

0.001

0.83 (0.28–2.48)

0.74

  

MSCT characteristics

CACS >100

8.68 (3.82–19.7)

<0.0001

  

16.4 (4.86–55.9)

<0.0001

5.57 (1.44–21.5)

0.01

CACS >400

6.46 (3.33–12.54)

<0.0001

  

4.65 (1.86–11.61)

0.001

  

Absence of plaques

0.03 (0.001–0.5)

0.02

  

0.02 (0.001–0.93)

0.04

  

Non-obstructive CAD

0.30 (0.13–0.73)

0.01

  

0.29 (0.09–0.85)

0.02

  

Obstructive CAD

12.19 (5.10–29.13)

<0.0001

6.38 (2.33–17.5)

<0.001

23.7 (7.89–70.9)

<0.0001

7.43 (2.1–26.7)

0.002

Single-vessel obstructive CAD

4.04 (2.12–7.71)

<0.0001

  

8.12 (3.39–19.46)

<0.0001

  

Multivessel obstructive CAD

4.25 (2.19–8.25)

<0.0001

  

11.46 (4.38–29.9)

<0.0001

  

No. of segments with

Any CAD

1.22 (1.14–1.3)

<0.0001

1.1 (1.001–1.2)

0.04

1.21 (1.11–1.31)

<0.0001

  

Non-obstructive CAD

1.18 (1.10–1.25)

<0.0001

  

1.17 (1.07–1.28)

0.001

  

Obstructive CAD

1.24 (1.14–1.36)

<0.0001

  

2.1 (1.6–2.6)

<0.0001

  
  1. CAD = coronary artery disease; HR = hazard ratio; CI = confidence interval