| All patients (n = 413) | |||
---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR (95% CI) | p Value | HR (95% CI) | p Value | |
Clinical characteristics | ||||
Age (>65 years) | 2.80 (1.64–4.79) | <0.001 |  |  |
Male gender | 1.35 (0.77–2.38) | 0.29 |  |  |
DM | 1.82 (1.06–3.14) | 0.03 |  |  |
Hypertension | 2.02 (1.07–3.80) | 0.03 |  |  |
Family history | 1.63 (0.96–2.77) | 0.07 |  |  |
Smoking | 1.84 (1.10–3.09) | 0.02 |  |  |
Hypercholesterolaemia | 1.76 (1.03–2.98) | 0.04 |  |  |
Obesity | 0.88 (0.49–1.59) | 0.68 |  |  |
Symptoms | ||||
Asymptomatic | 0.34 (0.16–0.71) | 0.004 |  |  |
Typical angina pectoris | 5.05 (2.95–8.63) | <0.0001 | 2.70 (1.46–4.97) | 0.001 |
Atypical angina pectoris | 0.53 (0.29–0.97) | 0.04 |  |  |
Dyspnoea | 1.62 (0.91–2.88) | 0.10 | 3.08 (1.55–6.09) | 0.001 |
MSCT characteristics | ||||
CACS >100 | 11.39 (5.7–22.6) | <0.0001 | 3.5 (1.62–7.57) | 0.001 |
CACS >400 | 6.11 (3.6–10.3) | <0.0001 |  |  |
Absence of plaques | 0.031 (0.006–0.17) | <0.001 |  |  |
Non-obstructive CAD | 0.28 (0.14–0.56) | <0.001 |  |  |
Obstructive CAD | 16.7 (8.46–33.1) | <0.0001 | 8.9 (4.0–19.59) | <0.0001 |
Single-vessel obstructive | ||||
CAD | 5.53 (3.3–9.32) | <0.0001 |  |  |
Multivessel obstructive CAD | 6.22 (3.6–10.7) | <0.0001 |  |  |
No. of segments with | ||||
Any CAD | 1.22 (1.16–1.28) | <0.0001 |  |  |
Non-obstructive CAD | 1.18 (1.12–1.24) | <0.0001 |  |  |
Obstructive CAD | 1.31 (1.22–1.41) | <0.0001 |  |  |
Interaction term | ||||
Obstructive CAD × DM | 6.71 (4.0–11.3) | <0.0001 |  |  |