Skip to main content

Table 4 Univariate and multivariate predictors of total cardiac events in all patients

From: Prognostic value of CT coronary angiography in diabetic and non-diabetic subjects with suspected CAD: importance of presenting symptoms

 

All patients (n = 413)

Univariate analysis

Multivariate analysis

HR (95% CI)

p Value

HR (95% CI)

p Value

Clinical characteristics

Age (>65 years)

2.80 (1.64–4.79)

<0.001

  

Male gender

1.35 (0.77–2.38)

0.29

  

DM

1.82 (1.06–3.14)

0.03

  

Hypertension

2.02 (1.07–3.80)

0.03

  

Family history

1.63 (0.96–2.77)

0.07

  

Smoking

1.84 (1.10–3.09)

0.02

  

Hypercholesterolaemia

1.76 (1.03–2.98)

0.04

  

Obesity

0.88 (0.49–1.59)

0.68

  

Symptoms

Asymptomatic

0.34 (0.16–0.71)

0.004

  

Typical angina pectoris

5.05 (2.95–8.63)

<0.0001

2.70 (1.46–4.97)

0.001

Atypical angina pectoris

0.53 (0.29–0.97)

0.04

  

Dyspnoea

1.62 (0.91–2.88)

0.10

3.08 (1.55–6.09)

0.001

MSCT characteristics

CACS >100

11.39 (5.7–22.6)

<0.0001

3.5 (1.62–7.57)

0.001

CACS >400

6.11 (3.6–10.3)

<0.0001

  

Absence of plaques

0.031 (0.006–0.17)

<0.001

  

Non-obstructive CAD

0.28 (0.14–0.56)

<0.001

  

Obstructive CAD

16.7 (8.46–33.1)

<0.0001

8.9 (4.0–19.59)

<0.0001

Single-vessel obstructive

CAD

5.53 (3.3–9.32)

<0.0001

  

Multivessel obstructive CAD

6.22 (3.6–10.7)

<0.0001

  

No. of segments with

Any CAD

1.22 (1.16–1.28)

<0.0001

  

Non-obstructive CAD

1.18 (1.12–1.24)

<0.0001

  

Obstructive CAD

1.31 (1.22–1.41)

<0.0001

  

Interaction term

Obstructive CAD × DM

6.71 (4.0–11.3)

<0.0001

  
  1. CAD = coronary artery disease; HR = hazard ratio; CACS: Coronary Artery Calcium Score; DM = diabetes mellitus; CI = confidence interval